About AHCC

AHCC (Active Hexoze Correlated Compound) is an extract from long-run culture of medicinal mushrooms (basidiomycetes).

This process has not been possible until now: especially during long periods of time it was difficult to maintain the colonies, but with the production of a germ-free environment, the breeding of basid mushrooms is already successful.

As a supplemental treatment of cancer therapies and other immunodeficiency states, AHCC can strengthen and stimulate the immune system for more effective healing.

The AHCC as a BRM

AHCC as an extract is a Biological Response Modifier (BRM) that stimulates and strengthens the patient's ability to defeat the cancerous condition. By strengthening the patient's immune system, cancer can be cured and can be eliminated more easily.

In the background of cancerous diseases there is a weakened immune system, which causes certain cells to be modified and cancerous lesions occur in the body.

In other words, cancer is a disease of the immune system. In the treatment of cancer, it is essential to eliminate abnormalities and alterations in the body's natural protective system.

AHCC restores and stimulates the immune system of patients, attacks cancer cells, activates and regenerates the weakened immune system.

Although chemotherapy can be considered drastic, it has various side effects such as strong nausea, frequent vomiting, hair loss, loss of appetite, decreased liver function. At the same time, the number of white blood cells and red blood cells in the blood decrease.

AHCC regulates and reduces the side effects of anticancer treatments, but it also promotes the effectiveness of chemotherapy. It improves the general well-being of patients, along with their quality of life. We believe that AHCC greatly contributes to the efficacy of anti-cancer therapies.

Based on the renewed AHCC recipe, from 2018 the product contains vitamin C, vitamin B6, and folic acid as well as Shiitake mushroom extract, so it can compete more effectively against immunodeficiency.

Production of AHCC

The center of the product manufacturing plant has been moved to the EU since 2018. O&A Trade Hungary Ltd. produces and distributes AHCC made from its own ingredients under controlled conditions, producing the AHCC natural dietary supplement.

O&A Trade Hungary Ltd. manufactures and markets natural dietary supplements and personal care products throughout Europe. Their offerings consist of officially validated, licensed products with registration number.

AHCC’s manufacturing unit is a registered manufacturing plant under European Union legislation. Our products are manufactured according to the strictest quality standards throughout the manufacturing process:

  • Compliance with ISO 22000:2005 standards
  • Food-GMP production system
  • Production according to HACCP system


Generally, the main component of the products made of mushroom is beta-glucan (β-glucan). By contrast, thanks to the unique production of AHCC it also contains ingredients that are not found in other similar products.

The basic ingredient of AHCC is acetylated alpha-glucan (α-glucan). Acetylated α-glucan has a relatively low molecular weight (average molecular weight of about 5000 daltons) and since molecular weight β-glucan ranges from tens of thousands to half a million, α-glucan is more easily absorbed than β-glucan. In addition, AHCC consists of a number of elements derived from the cultivation and fermentation of basidial fungi.

For AHCC, mycelial plants of basalid fungi are grown for a longer period of time. The AHCC's special ingredients are obtained through the enzymatic reaction of these medicinal mushrooms with different elements. The presence of several new components, such as acetylated alpha-glucan, has been demonstrated in the AHCC composition.

Ingredients / capsule:

AHCC with 40% alpha-Glucan extracted from Shiitake mushroom, capsule shell: gelatine, ascorbic acid (vitamine C), anti caking agents: Aerosil (silica), Magnesium stearate, microcrystalline cellulose 101, vitamine B6 (Pyridoxal 5-phosphate), Folic acid.

Active substances / capsule:
AHCC extracted from Shiitake mushroom 300 mg
of which alpha-Glucan 120 mg
Vitamine C 100 mg*
Vitamine B6 2,8 mg**
Folic acid 400 mcg**

* 125% of the daily nutrient reference value for adults (NRV)
** 200% of the daily nutrient reference value for adults (NRV)


Suggested consumption

1x1 capsule per day for adults, preferably before meal, should be taken with a glass of water

WARNING: Please do not exceed the recommended daily dose, i.e. 1 capsule.


Basidium mushrooms have been consumed by people for a long time. In AHCC this is also the primary raw material used. The best safety certificate is that many people use it on a regular basis since trying it.

For several months individual and toxicity tests, mutagenicity and safety studies as well as numerous studies on animals and with humans under normal conditions of life have shown that AHCC is a non-toxic, safe food product suitable for human consumption. Indeed, no adverse reaction to a human body since its introduction in 1989 has been reported.

Keep out of the reach and sight of children. The dietary supplement is not a substitute for a balanced, mixed diet and a healthy lifestyle. Do not store above +25 °C. Store it in a dry, sun-protected space.

Positive effects

AHCC (Active Hexose Correlated Compound) is a natural dietary supplement with vitamine B6, vitamine C and Folic acid. Vitamine B6, vitamine C and Folic acid contibute to the proper function of the immune system. Folic acid contributes to normal haematopoiesis, vitamine B6 contributes to normal red blood cell formation while vitamine C contributes to to the protection of cells against oxidative stress.

  • activation of immunity
  • anti-cancer effect
  • reduces the side effects of chemotherapy
  • provides protection against infections
  • it’s beneficial effect on diabetes is also known

In Japan the AHCC is a food approved by the FDA (US Food and Drug Administration) for human consumption. Its use is common and licensed in China, Thailand and South Korea.

In addition, AHCC provides not only a survival option for patients who can not be operated or have cancer in a chronic, progressive phase, but also helps to maintain their physiological functions even if their condition does not show any improvement from a medical point of view.

AHCC treatment helps patients live a mentally and physically complete, high quality life. In the second week following the onset of AHCC use patients reported a significant improvement in their quality of life: improved appetite, lighter sleep, decreased hair loss in chemotherapy.

The experimental results of AHCC show:

  • immune stimulating effect
  • reducing the adverse effects of cancerous diseases
  • reduces the side effects of chemotherapy
  • protects against infections
  • diabetic effect

In addition, AHCC is also successful in the treatment of the following diseases:

Liver disorders, diabetes, inflammation, hypertension, hyperlipidemia (high blood fat level), regulation of internal separation, Hepatitis, Myeloma, Rhabdomyosarcoma, liver cancer, gastric cancer, colon cancer, breast cancer, thyroid cancer, ovarian cancer, testicular cancer, prostate cancer, oropharynx, kidney cancer, pancreatic cancer, HIV infection, diabetes, heart disease, prolonged stress, and activities done in a toxic environment.